The PQQ and CoQ10 Revolution

Why combining these two supplements has taken the supplements industry by storm

supplementsThere’s a lot of  buzz surrounding the dietary supplement PQQ which has stormed onto the market in the last few years due to its anti-ageing properties – and in its ability to help stimulate cognitive function. While PQQ is somewhat effective on its own, when it is combined with the related compound  – the relatively well-known coenzyme Q10 (CoQ10) – even better results have been shown.

This is not just backed up by anecdotal evidence (though there’s plenty of that), but a number of scientific studies that have measured the relative effectiveness of these two supplements.

One Japanese study  in 2007 measured the cognitive functions of 71 middle aged persons. The first group took 20mg of PQQ daily and demonstrated improved cognitive ability compared to the control group (placebo). A third group was administered 20mg of PQQ and 300mg of CoQ10 – and they demonstrated an even greater cognitive improvement. PQQ and CoQ10 are both involved in mitochondrial energy production, so these results are probably not that surprising. As a result of these encouraging studies, it’s no surprise that many people have been taking both supplements simultaneously.

So why not just buy PQQ and CoQ10 separately?

There is absolutely nothing wrong (and plenty good) with taking PQQ and CoQ10 separately and most people have usually begun with one product before adding the other.

The most basic reason is cost.

The average online cost of a bottle of PQQ (a month’s supply) is around $20 if purchased in bulk. Individually purchased bottles can cost upwards of $45.

Similarly, purchasing CoQ10 separately will set you back somewhere between $25 and as much as $50.

Then, of course, you have to add shipping costs for TWO products.

There are other things to consider too.  Of the four products we have reviewed below, all of them have added extra ingredients to add value.

pillsFor example, Life Extension have added PrimaVie® Shilajit fulvic acid complex to their Super Ubiquinol which they claim enhances the effect of both supplements.

Mito Osteo’s rather ingenious addition is the well-known joint pain relieving supplement glucosamine hydrochloride.

The final reason is, really, that it’s just easier. There’s never any confusion as to which one you’ve taken (if you’re like me and take multiple supplements and medication in the morning it can get pretty confusing keeping track) and no problems with your stock being out-of-synch.

How do the leading brands of these anti-aging supplements compare?

In the last few years, a number of supplements companies have sought to combine PQQ and CoQ10 into a single dose, reducing costs and waste for consumers.

In most instances, additional products have been added to enhance their value.

Stay Home Shopping has a look at four leading products that have successfully combined both ingredients; Super Ubiquinol (Life Extension), Mito Osteo (Gold Medal Health), Ultra Accel (Primal Force) and Unfair Advantage (Bulletproof).


ProductDescriptionPQQCoQ10Best Price
Super Ubiquinol CoQ10 with BioPQQ
super ubiquinol
By adding PrimaVie® Shilajit fulvic acid complex, leading supplement’s brand Life Extension claim to have nearly doubled the effect of the CoQ10 alone.

The product also includes gelatin and beeswax amongst other ingredients so may not be suitable for vegans.

Each bottle contains 30 soft gels (1/day). Single bottles retail for $40.50 but the best price is obtained via autoship or with a minimum order of 10 bottles.

(10 bottle minimum)
Mito Osteo
Gold Medal Health's Mito Osteo adds glucosamine hydrochloride to form a unique combination that aids in joint pain and osteoarthritis in addition to the benefits associated with PQQ and CoQ10.

Recommended dosage is 2 caps per day and 60 are included in each bottle. All ingredients are plant based and so the product is suitable for vegans and those with allergies.

A single bottle retails for $69.95, with the best price of $37.49 available with a minimum order of 4.

With double the dosage of PQQ and double or more CoQ10 of its competitors, Mito Osteo clearly offers the best value for money.

(4 bottle minimum)
Ultra Accel
Ultra Accel by Primal Force adds mixed trocotrienols (Vitamin E) to boost cell's antioxidant strength. The dosage represent about 20% of daily recommended intake.

Each bottle contains 30 soft gels (1 month).

A single bottle retails for $69.95 (+ shipping) with the best price of $55.96 (free shipping) per bottle available through a minimum 3 bottle order every three months on autoship.

Unfair Advantageunfair_advantage_ampules_1Bulletproof’s Unfair Advantage uses a "colloidal delivery technology for maximum effect”, which they claim makes their extremely low level CoQ10 more effective. There are no other active ingredients listed.

The product comes in a carton of 30 mini-shots with a recommended dosage of 1-2 shots (enhanced mental performance) or 2-4 shots (enhanced sports performance).

Even at the rate of 1 shot per day, Unfair Advantage appears to offer the worst value for money with a carton priced at $59.95. Clearly, taking 2 or more mini-shots per day would make this a very expensive product.